Senn Chemicals offers a variety of products and services to support discovery, development and manufacturing needs of our clients. Whether your needs are small quantities for R&D or for pre-clinical development, or multi-kilogram quantities of key intermediates / APIs produced under cGMP, Senn Chemicals is capable of fulfilling them.
Customer Need | Senn Service |
Discovery | Ready-to-use reagents & building blocks |
| Synthesis of custom building blocks & synthons |
| Synthesis of lead compounds, focus libraries & analogs |
Development | Process research and development |
| Synthesis of reference compounds, analytical standards |
| Gram or kilo-scale preparation (GMP if needed) |
GMP Manufacturing | Process scale-up and optimization |
| Multi-kilo to ton-scale production under cGMP |
| Process validation |
Discovery Services
Senn Chemicals supports discovery scientists and medicinal chemists in their efforts of designing, synthesizing, optimizing and developing new chemical entities as follows:
- Senn Chemicals Catalog lists more than 1500 ready to use, high-quality building blocks and reagents ranging from amino acid derivatives, biochemicals, carbohydrates, chromogenic substrates to functionalized polymers.
- For client convenience, we also offer cost-effective and fast synthesis of customized building blocks, synthons or intermediates, performed at our Swiss or US facilities.
Development Services
Route selection, synthesis design and process development:
As the project progresses through early development, we undertake concurrent chemistry development and process optimization exercises leading to manufacturing routes that are safe, efficient, scalable and environmentally friendly. We take into consideration, cost effectiveness derived from selection of appropriate starting materials, solvents and reagents, and using risk mitigated chemistries. Senn Chemicals is well aware that documentation filing and quality related services are strongly dependent on the chosen synthesis and our route selection will always consider these parameters
Scale up and small scale GMP-synthesis:
Our highly flexible GMP manufacturing capability ranges from a few grams to hundreds or even thousands of kilograms. Our streamlined documentation and project management guarantees an excellent information flow between the R&D, pilot plant and production departments. The state of the art scale-up capabilities supports, process validation for your project as well.
Synthesis of impurities, metabolites and reference standards:
Our R&D has the knowledge and expertise to synthesize and characterize the most challenging impurities, metabolites of your API as well as reference standards.
cGMP Manufacturing Services
To support our client’s cGMP manufacturing needs Senn Chemicals operates a state-of-the-art production facility located in Dielsdorf, near Zurich Switzerland. Based on decades of experience in running hundreds of manufacturing campaigns, covering a wide variety of chemistries, we take pride in our commitment to produce your products cost effectively within you specification.
Analytical and Regulatory Services
As a complement to our chemistry and manufacturing services, Senn Chemicals offers a full range of analytical and regulatory related services. Working in concert with our client’s counterparts, our team of experts set up a strategic path for defining and generating data and documentations to support client’s product development and registrations process.
- Specifications
- Analytical methods development & validations
- Reference standards – synthesis & characterization
- Significant impurities – identification & synthesis
- ICH stability studies
- Stress and photo induced stability studies
- Cleaning methods development and validations
- Evaluation of Critical Control Points and Proven Acceptable Ranges
- Process validations
- Documentation: DMF, CMC, etc
ONLINE CATALOG 
