Expertise Spanning Diverse Chemistries
Even though Senn Chemicals has a strong focus on peptides we have amassed over the past decades a vast chemical knowledgebase in the manufacturing of diverse molecular classes.
This unique strength in chemistry enables Senn Chemicals to solve manufacturing challenges without limitation to chemical boundaries. We can offer a variety of products from our collection, or cost-effectively produce new chemical entities to suit your needs.
Senn Chemicals has developed novel technologies based on chiral synthesis, enzymatic resolution and other techniques to produce complex organic molecules in high optical purity.
Some of the chemical reactions commonly used in our facilities are given below:
Type of reaction | Selected Examples |
Alkylation | Williamson, Friedel-Crafts |
Acylation | Schotten-Baumann, Friedel-Crafts |
Amidation | -CN to CONH2, -COOH to CONH2 |
Amination, Aminoalkylation | Leuckart-Wallach, Mannich |
Carboxylation | Kolbe-Schmitt, Grignard |
Asymmetric synthesis | Alkylation, Reduction, Oxidation, Epoxidation (Sharpless), Resolution |
Condensation | Malonic, Knoevenagel, Dieckmann |
Coupling | Active esters, Mixed anhydrides, Uronium salts |
Cyclisation | Dieckmann |
Degradation | Hofmann, Curtius |
Esterification /Transesterification | Catalytic methods, Azeotropic methods Isobutene chemistry |
Glycosidation | Königs-Knorr, Fischer, Michael |
Halogenation | Chlorination, Bromination |
Organometallic Chemistry | Grignard |
Oxidation | Bayer-Villiger |
Polymerization | NCA |
Reduction | Hydrogen transfer, NaBH4, Catalytic, reductive amination |
Sulfonation, Chlorosulfonation Phosphorylations | |